Tex (Woody Allen), a kosher butcher from New York under the witness protection program in Arizona, has a problem. He has just killed his wife, Candy (Sharon Stone), in a jealous rage, after discovering she's having an affair with the local sheriff (Keifer Sutherland). He's cut her body into pieces and has taken them to the Mexican border, but he's lost one of her hands! A blind old village woman stumbles upon the hand, hits her head, and miraculously regains her eyesight. Soon thousands are flocking to the local church to see the hand of the 'Madonna' and miracles are granted to all who ask. But the village priest (David Schwimmer), who is in love with the town hooker (Maria Grazia Cucinotta) senses that the hand's origin is not quite 'virginal'. Tex, the Sherrif and the Priest all want something done with the hand, and the unpredictable outcome proves to be both magical and hilarious.